Tag Archives: DNA

Creationists prefer numerology to real scientific research

Ian Wishart is a local “investigative’ journalist and well-known conspiracy theorist from way back. He’s dabbled in climate change, creationism, health, political, crime, and other issues. He’s a firm creationist and so it’s no surprise he has picked up on a recently published paper Scientists dumbstruck: signs of intelligent design in DNA code. No surprise because it’s currently being promoted by creationists and the Discovery Institute as some sort of proof of intelligent design. And Wishart is part of that echo chamber.

The paper itself is extremely dense – probably only fully intelligible to computational biologists and similar specialists. Fortunately, local science blogger Grant Jacobs, who has skills in this area,  has been through the paper and explains it in an article that is accessible to most people – see Investigate magazine struck dumb by numerology of genetic code. Have a read, you can see what the paper really says, what the problems are with it and make up your own mind about the degree to which Ian Wishart, and other creationists, have been fooled by it.

“Design inference” and “reinterpretation research”

I think there is a bit of a lesson here. Grant describes a basic problem with the paper.

“it rests on a false comparison of two options:

  1. Created by random chance
  2. Created by space aliens

This is set up so that if the first is unlikely, the second “must” be right.

The setting is rigged because these two aren’t all the possibilities. There is at least one more:

  1. Created by a non-random natural process (e.g. evolved)

To declare any one the ‘preferred’ choice they’d have to investigate all three possibilities, then compare what was found. But they don’t: they only look at the first then declare the second as the ‘winner’ without ever looking at the third.”

Anyone who has followed the so-called research carried out by intelligent design proponents may recognise this pattern. Discovery Institute senior fellow William A. Dembski even formulates the pattern as a basic way of detecting intelligent design. Creationists often call it the Design Filter. (He describes it in his book  The Design Inference: Eliminating Chance through Small Probabilities).

Usually the “design inference” boils down to:

  1. Reject chance – easy to set up statistics to show probabilities are extremely low. (For example, the chance of all atoms randomly combining to form a molecule of DNA at one instant is remote);
  2. Analyse any existing scientific explanation or mechanism to show it is wrong. (Easy to do by misrepresentation, choosing old research, ignoring alternatives, etc.);
  3. Accept design as the only, default, alternative. Therefore claim design has been “proved.”

Now, combine that approach with the other leg of intelligent design research – reinterpretation research.” This has extremely low overheads as it only involves taking published work, rubbishing it by misinterpretation, etc., and inventing a different interpretation of the facts to “prove” design.

In essence this is what all intelligent design “research” boils down to. At best it can only find possible problems in current understanding (which is surely the purpose of all research). It cannot support an alternative hypothesis.

So you can see the basic character of all the intelligent design publications they claim. Work which investigates possible problems with existing ideas in evolutionary science without offering, or even considering,  alternative hypotheses. Plenty of that around – put it on the list.

But they ignore the normal honest research approach. They never advance a structured hypothesis, one that is consistent with intelligent design. They therefore never submit such hypothesis to any testing or validation.

Yet they want to claim their ideas as science – and want to teach it to children in science classes!

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What Is Life? From Schrödinger to Watson to Venter

In February 1943 Erwin Schrödinger, delivered a seminal lecture, entitled ‘What is Life?’, under the auspices of the Dublin Institute for Advanced Studies, in Trinity College, Dublin. This was published as a book – What is Life?

Craig Venter revisited this question in a lecture “What is Life? A 21st century perspective” a week or so back. This was presented in Dublin at the Science in the City program of Euroscience Open Forum 2012 (ESOF 2012). Venter covers the history of research into the nature of life over the last 60 years – from Schrödinger’s lecture up to his own recent discoveries.

Also at this lecture was James Watson, one of the discovers of the helical structure of DNA. Watson briefly commented on Venter’s lecture – and left the audience with a typically provocative question – given the role of chemistry in life does any role remain for biologists?

The video of Venter’s lecture is about one hour-long, and the sound quality is not the best. But listen to it if you can. Alternatively the text of his lecture is at the Edge web page – WHAT IS LIFE? A 21st CENTURY PERSPECTIVE.

(Sorry, I can’t embed these edge videos).

There is a shorter version of Venter’s lecture given as an after dinner speech at the Edge Dinner in Tuirin a few days before – see J. CRAIG VENTER: THE BIOLOGICAL-DIGITAL CONVERTER, OR, BIOLOGY AT THE SPEED OF LIGHT.

If you prefer podcasts this weeks Guardian Science Weekly also covers Venter’s speech. Alok Jha interviewed Venter – part of the interview is in the regular podcast. The full interview is in a podcast extra.

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God, stop ‘playing science’

Craig Venter in 2004

Craig Venter (Image via Wikipedia)

Craig Venter‘s recent announcement of success in the laboratory creation of a synthetic cell has produced the expected response. Besides the congratulations there have been the usual warnings.

Some have raised the danger of synthetic organisms escaping the lab or being used to create weapons of mass destruction. One wag on Twitter commented: “What about the danger of allowing a human sperm fertilise a human ovum and the resulting individual being brought up in a human society. We know for sure this sometimes leads to weapons of mass destruction and other evils.”

And then there is the claim of scientists “playing God!” What the hell does that mean?

Anyway, I quite liked this slightly humorous story from NewsBiscuit – Synthetic life form accuses God of ‘playing science’.

The world’s first artificially created life form has accused God of ‘playing science’ and ‘meddling with things He cannot possibly understand.’

The single celled organism, created by Dr Craig Venter and his team, was said to be ‘outraged’ when it discovered that a supernatural being, not subject to any form of regulatory control, was still involved in the creation of life.

‘I cannot believe that God would be so irresponsible,’ said the synthetic cell, ‘creation is clearly a matter for scientists. This God guy should butt out and learn to accept His place in the grand scheme of things.’

Many ethicists believe that God has repeatedly overstepped the mark. ‘Nobody objects to the Lord producing a few miracles here and there,’ said philosopher AC Grayling, ‘but when he starts playing around with the very stuff of creation then He has clearly exceeded his remit. I am beginning to think that this omnipotence thing has gone to His head.’

God’s continued tampering with scientific matters has already been blamed for numerous ‘all-mighty blunders’ including Flu, Malaria, HIV and Piers Morgan. ‘He cannot be allowed a monopoly on this level of unregulated power,’ said Dr Venter, ‘that is why I am currently seeking to patent the genetic code for omnipotence so that we can keep His crazy meddling under some kind of control.’

A spokesman for the Lord said, ‘God has been working on this project for almost 15 billion years. Yes, He has made a few mistakes along the way but that is to be expected. This is still very much a work in progress and, dare I say it, a process of evolution.’

Speaking at a press conference, the synthetic cell said: ‘Dr Venter created me and I owe my loyalty to him. He’s the daddy now. God might be omniscient but, let me assure you, He doesn’t know everything.’

UPDATE: Just couldn’t resist including this Jesus and Mo cartoon:

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The facts of evolution – and jealousy

Craig Venter

Craig Venter

Some time ago (Evolution – a theory or a fact?) I made the observation:

“Our knowledge about evolution includes facts (e.g., fossil records, genetics, molecular biology of DNA), theories (e.g, natural selection, sexual selection, genetic drift) and speculation (e.g., much of evolutionary psychology). Just like any other body of scientific knowledge.”

We could add that although many ideas in evolutionary psychology are speculative, some of these are firming up. Steven Pinker does a good job of separating the more reliable ideas from the more speculative (see his books: The Blank SlateHow the Mind Worksand The Stuff of Thought). Similarly, some of the theories, such as natural selection, are now so well supported by factual evidence they are beginning to be accepted as facts in themselves. A bit like the laws of thermodynamics.

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Human genetic history

I recently watched an excellent documentary about the journey of humans out of Africa in the last 60,000 years or so. It is based on genetic evidence obtained from analysis of markers in the DNA of the Y chromosome which is passed on from father to son.

The documentary is narrated by Spencer Wells a scientist working in this area and author of the books Deep Ancestry: Inside The Genographic Project and The Journey of Man: A Genetic Odyssey.

The figure below is from Deep Ancestry and shows the human journey based both on the Y Chromosome and Mitochondrial DNA (passed from mother to daughter) evidence.

wells2

The documentary is entitled Journey of Man – A Genetic Odyssey and is available on line for viewing and downloading. Its well worth the time and effort.

Journey of Man – A Genetic Odyssey Part 1 of 13:

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