Tag Archives: SciBlogs

Are fluoride researchers sacked for their findings?

Dr Phyllis Mullenix – employment terminated because of her fluoride research or other reasons? (Image credit: NYC Coalition Against Artificial Fluoridation)

Heard the one about the scientist who was doing excellent research but was sacked by her Institute because her discoveries shattered the prevailing “scientific orthodoxies?”

Yes, it is a common claim. Often made by activists promoting conspiracy theories.  But it is an easy one to make and it is always worth checking the facts in such cases.

Of course, the anti-fluoridation movement is no exception – they claim that a number of “anti-fluoridation scientists” have been sacked for their work. Here I will just look at one of these stories – that of Dr Phyllis Mullenix.

The Mullenix story

A few facts.

Phyllis Mullenix was working for the Forsyth Research Institute in Boston. In her time there, she researched several possible neurotoxicants but made only one study on fluoride which was published in 1995. The paper is:

Mullenix, Phyllis J., DenBesten. Pamela K., Schunior, A., & Kernan, W. J. (1995). Neurotoxicity of sodium fluoride in rats. Neurotoxicology and Teratology, 17(2), 169–177.

This paper has become central to claims made by anti-fluoride campaigners that community water fluoridation lowers IQ in children.

However, this paper is not relevant to community water fluoridation because of the very high concentrations of fluoride used (0, 75, 100, 125 and 175 mg/L in drinking water fed the rats). That such levels are unrealistic was shown by her own report that “the 175 ppm level .  .  . resulted in dehydration and the death of 10 of the exposed animals within 10 days.” Half of the 21 animals exposed died within 10 days!

For comparison, the recommended concentrations for community water fluoridation are usually less than 1 mg/L. But it is interesting that when anti-fluoride campaigners tell Mullenix’s story they rarely mention the concentration she used.

Mullenix did lose her job at Forsyth. A unanimous meeting of senior staff members on April 19, 1994, recommended she not be reappointed to her position. She was a staff associate and employment was usually guaranteed for 12 months at a time. Renewals would have depended on several factors, including the level of funding the employee was able to attract from research grants. Mullenix was informed by letter on May 31, 1994, that the Board of Trustees had approved the recommendation from senior staff members that her appointment would not be renewed.

So, she lost her job – but technically was not sacked – just not reappointed.

Why was her employment not renewed? 

Anti-fluoride campaigners rely on books like “The Fluoride Deception” to support their conspiracy theories

Depends if you believe there was a conspiracy against fluoride research.

Here are some of the conspiracy stories that are floated:

Chris Bryson says in his book The Fluoride Deception:

“PHYLLIS J. MULLENIX. A leading neurotoxicologist hired by the Forsyth Dental Center in Boston to investigate the toxicity of materials used in dentistry. In 1994 after her research indicated that fluoride was neurotoxic, she was fired.”

This claim has been repeatedly presented in articles and submissions by anti-fluoride activists. For example:

She went from being a leading neurotoxicologist at a Harvard affiliated research institute to an industry pariah. This assignment and her findings ruined her career as a grant-funded research scientist.”

Dr Phyllis J Mullenix should be a household name. She was sacked for her work proving Aluminium and Fluoride act synergistically to damage your brain and that of your unborn child.”

Within days of learning that her study was accepted for publication, Dr [Phyllis] Mullenix was fired from the Forsyth Dental Center.  She has received no grants since that time to continue her research.”

Dr Phyllis Mullenix was sacked from the Forsyth Dental Center, where she was head of the toxicology department, for publishing research in Neurotoxicology and Teratology showing that fluoride can adversely affect brain function. She had been warned: “If you publish this information, we won’t get any more grants from NIDR” (from which the institute got most of its money).

And I could go on. And on. There is no shortage of such claims promoted as arguments against community water fluoridation.

But here are some facts.

I have gone to the legal document presented to the US District Court, D, Massachusett on November 13, 1996. These relate to a case brought by Mullenix against Forsyth claiming discrimination and retaliation for her legal actions.

Mullenix’s complaint:

“alleges that Forsyth discriminated against Dr. Mullenix on the basis of her sex, denied her equal pay and one or more promotions and retaliated against her for seeking legal redress during her employment at Forsyth as a Staff Associate from 1982 to 1994.”

The document, Mullenix v. Forsyth Dental Infirmary for Children, is quite long and full of legalese which I would never pretend to understand. But it certainly makes clear that the complaint by Mullenix and the response by Forsyth have nothing to do with fluoride or fluoridation.

Fluoride is mention only a few times:

“Dr. Mullenix asseverates that no one at Forsyth ever questioned the quality of her work or that her fluoride research did not lie within Forsyth’s mission. (Docket Entry # 102, Mullenix Affidavit).”

And:

“Dr. Mullenix contends that Dr. Taubman “called Dr. Mullenix `hysterical’ because he disagreed with her research.” (Docket Entry # 102, p. 18). Dr. Mullenix recites Dr. Taubman’s alleged statement while explaining what she said to Dr. Hay during a conversation a few days after giving a seminar on fluoride research. According to Dr. Mullenix, Dr. Hay mentioned that “Marty Taubman in particular was very irate about the data that was presented …” and that “Marty Taubman had indicated that I was hysterical in my reporting.” (Docket Entry # 98, Mullenix Deposition).”

It appears Mullenix made the complaint about use of the word “hysterical” together with apparently sexist remarks made by colleagues (relating to clothing and the employment rights of women who had husbands) as evidence of a hostile and sexist work environment.

This document outlines the various complaints made by Mullenix – and clearly, they did not relate to fluoride or, directly, to her findings about fluoride. In fact, it says:

“Dr. Mullenix asserts that the only reason other than gender which explains Forsyth’s actions is that it acted in retaliation for Dr. Mullenix’ seeking legal redress.”

Mullenix took her initial legal action because she had been denied a promotion and subsequently claimed Forsyth had retaliated against her because of her initial threat of legal action if her promotion was declined (it was and she did take legal action) and then the actual legal action.

I have focused on Mullenix’s version here because they do make clear that her fluoride research and findings were not involved in any retaliation by Forsyth. The institute’s version, of course, seeks to justify their actions. While there is some reference to her research interest not coinciding strongly with the Institute’s interests, their evidence relates almost completely to salaries for male and female staff members, the responsibilities of the staff associate position that Mullenix occupied, and the extent of funding Mullenix was able to attract.

I have no idea of the legitimacy of Phyllis Mullenix’s complaints or the legitimacy of Forsyth’s rebuttals. Nor do I know what the final outcome of her legal action was.

Mullenix’s complaints could very likely have been genuine. Even today women do get discriminated against in employment and salaries. Their complaints are often disregarded or treated in a sexist way. “Uppity” women can face retaliation. And things are better now than they were in the 1980s and 1990s. It is very likely Mullenix was granted an out-of-court settlement.

But one thing I am sure of – she was not “sacked’ for her fluoride research or publication of her fluoride paper. Any complaint made by colleagues about that work would have been perfectly normal and expected – and she herself, at the time, did not attribute any retaliatory action to her fluoride research.

So, yet another case where it pays to check the claims made by anti-fluoride activists.

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Fluoridation and cancer

Yes, you have. And one lie is the claim that fluoridation causes cancer. Image credit: Have You Been Lied to About Fluoride?

We all know the phrase “Lies, damned lies, and statistics.” If nothing else, this should warn us not to take on faith arguments which rely on statistical analysis for their credibility. Wikipedia uses this phrase to illustrate the “persuasive power of numbers, particularly the use of statistics to bolster weak arguments.”

Unfortunately, the scientific literature is full of weak arguments bolstered by statistics. It’s another case of “reader beware.” Do the statistical analyses used really support the argument? And how good was the statistical analysis anyway?

Unfortunately, scientific papers with poor or inappropriate statistical analyses often get used to bolster arguments in the political field. Anti-fluoride campaigners do this all the time. I illustrated this for the “fluoridation caused ADHD” argument in my articles ADHD linked to elevation, not fluoridation and ADHD link to fluoridation claim undermined again.

Another paper often used by anti-fluoride campaigners is that of Takahasi et al., (2001). They cite this to support their “fluoridation causes cancer” argument. For example, the prominent anti-fluoride activist Karen Favazza Spencer did this recently in a Facebook post quoting from Tkahashi et al., (2001):

“Cancers of the oral cavity and pharynx, colon and rectum… were positively associated with ‘optimally’ fluoridated drinking water.”

Well, how justified is that quote? How reliable was the statistical analysis used by these authors to arrive at that claim?

Takahashi et al., (2001)

In fact, their statistical analysis was poor. They considered only fluoridation as a factor. When we consider other likely factors the statistical analyses show no significant association between these cancers and fluoridation.

Let’s have a look at the paper and the statistical analysis.

The paper is:

Takahashi, K., Akiniwa, K., & Narita, K. (2001). Regression Analysis of Cancer Rates and Water Fluoride in the USA based Incidence on IACR / IARC ( WHO ) Data ( 1978-1992 ). Journal of Epidemiology, 11(4), 170–179.

Briefly, it searched for possible statistically significant associations between the incidence rates for a whole range of cancers and the extent of fluoridation. It used fluoridation extent and cancer incidence data for three US states and six US cities. Other factors were considered only for lip cancer where sunshine extent was included in the analyses.

I set out to repeat their statistical analysis, including some other relevant factors. However, the data they used for cancer incidence in 1978-1992 is not available on-line. But there are data sets available for more recent years.

Here I use the cancer incidence data for 1993-1997 taken from the WHO, International Agency for Research on Cancer publication Cancer Incidence in Five Continents Vol. VIIIThis lists cancer incidence for 58 body sites but I restricted my analysis to eight of the body sites for which Takahashi et al., (2001) reported significant associations with fluoridation.

Are any of these cancers significantly associated with the extent of fluoridation?

Well, yes, two are at the 5% level (p < 0.05) – cancers of the rectum and bladder. The table lists values for the probability p value produced by linear regressions. The p values for cancers at all the body sites considered is also significant – but only for females.

Cancer site p – Male p – Female
Lip 0.750 0.825
Oesophagus 0.427 0.285
Colon 0.090 0.146
Rectum 0.037* 0.048*
Bone 0.784 0.147
Prostate 0.639
Bladder 0.015* 0.031*
Thyroid 0.806 0.519
All sites 0.250 0.020*

Takahashi et al., (2001) found significant associations for rectum and bladder. But also for Colon, bone (male), oesophagus (female), prostate (male) and lip. This difference is not too surprising as I used a different, more recent, data set. Also, correlations do not mean causation, they can occur by chance (1 in 20 samples) and other factors are more than likely involved (see below).

Another difference is that I used simple linear regressions. Takahashi et al., (2001) transformed both fluoridation extent and cancer incidence to logarithms but their explanation for this is inadequate.  Such transformations are not normally applied unless there is evidence that a relationship is nonlinear.  Takahashi et al., (2001) did not give any evidence for this and there was no evidence for it in the data set I used.  Neither was there any evidence of patterns in the residual values from the regression analysis – another sign that simple linear regression was valid.

What about the influence of other factors?

One of the biggest complaints I have about the use of regression analysis in studies like this is that very often other factors are ignored. Takahashi et al., (2001) considered only sun shine extent – and then only for lip cancer.

I think the restriction to consideration of only fluoridation is naive. In fact, probably indicating a bias and a desire to confirm it. It is extremely unlikely that all, or even most, of the specific cancers considered have a single cause – fluoride. And it is unlikely that a single factor would explain all the variability in the cancer incidence data.

Also, fluoride could be acting as a proxy for more relevant factors. The ADHD relationship with the extent of fluoridation is an example. In my paper Attention deficit hyperactivity disorder prevalence associated with altitude but not exposure to fluoridated water*, I showed that fluoridation extent is significantly correlated with mean altitude. When altitude was included in a multiple regression there was no significant association of ADHD with fluoridation.  This suggests that, in fact, the fluoridation data was really a proxy for something else – in this case, altitude – which Huber et al (2015) reported is associated with ADHD prevalence.

I am not intending here to narrow down the most likely factors which are associated with cancer at all these body sites. I simply want to check how significant any association with fluoridation is when other possible factors are included.

Geographic factors are worth considering – not because they necessarily have a direct influence. But because they may act as proxies from environmental, population density and industrial concentration factors which could be important. So I included data for mean elevation, mean latitude and mean longitude together with the extent of fluoridation in multiple regressions of the eight cancers above as well as for all the body sites data.

Using adjusted R square values to test for a fluoridation contribution

Rather than attempting to identify significant correlations with different factors for different cancers, I used the method of judging what effect inclusion of fluoridation extent had on the explanatory power of regression models which included the geographic factors. Jim Frost describes this approach in his article Multiple Regression Analysis: Use Adjusted R-Squared and Predicted R-Squared to Include the Correct Number of Variables

Briefly, he describes problems with the R squared value:

“Every time you add a predictor to a model, the R-squared increases, even if due to chance alone. It never decreases. Consequently, a model with more terms may appear to have a better fit simply because it has more terms.”

Include more factors and you could simply be modelling random noise in the data.But the adjusted R-squared  overcomes this because it adjusts for the number of predictors in a model:

“The adjusted R-squared increases only if the new term improves the model more than would be expected by chance. It decreases when a predictor improves the model by less than expected by chance. The adjusted R-squared can be negative, but it’s usually not.  It is always lower than the R-squared.”

These examples below of multiple regression output including fluoridation and excluding fluoridation in the models illustrate where adjusted R square values are reported:

The table below lists the adjusted R square values for multiple regressions:

  • +Fl included fluoridation extent, mean elevation, mean latitude and mean longitude, and
  • -F included only mean elevation, mean latitude and mean longitude.

Comparing the adjusted R square values for +Fl and -Fl tells us about the effect of including fluoridation extent on the models:

  • Where the value for +Fl is larger than for -F then the extent of fluoridation improves to model more than would be expected by chance.
  •  Where the value of +Fl is smaller than for -F then the extent of fluoridation improves to model less than would be expected by chance.

Male

Female

Cancer site + Fl – Fl + Fl – Fl
Lip 0.170 0.242 0.685 0.649
Oesophagus 0.809 0.842 0.558 0.612
Colon 0.842 0.771 0.681 0.659
Rectum 0.357 0.455 0.616 0.692
Bone 0.451 0.527 0.625 0.700
Prostate -0.350 0.130
Bladder 0.860 0.863 0.530 0.606
Thyroid 0.434 0.544 0.801 0.824
All sites 0.622 0.676 0.846 0.865

The table shows that adjusted R square values are greater (red) when fluoridation extent is not included in the regression model for all cancer sites except the colon and female lip. That indicates that these cancers are not associated with fluoridation extent. That the simple regression results alone  for fluoridation extent in the case of rectum and bladder cancer (and all sites female cancer) are misleading.

The colon and female lip cancer are exceptions – but the fact no significant association was found for fluoridation extent alone (first table) suggests something more complex is occurring here. It could be that the selected geographic factors have very little role in these cancers and inclusion of more relevant factors is needed.

Conclusion

The associations of fluoridation extent with various cancers reported by Takahashi et al., (2001) disappear when we consider other more relevant factors. Therefore, the use of this study by anti-fluoride campaigners to claim fluoridation is responsible for cancer is misleading. Not that I expect, from their past record, they will stop doing this.

More generally this is yet another example showing that readers should beware of putting too much faith in simple statistical analyses reported in scientific papers – even those published in respectable journals. It is just too easy to use statistical analysis to confirm a bias.

We should all keep in mind the phrase  “Lies, damned lies, and statistics” and treat such reports critically. If possibly checking out the extent to which other factors have been considered. Even where significant correlations are reported we should check how useful such correlations are at explaining the variations in the data.


*The full text of this paper is not yet available as it is undergoing journal peer review. However, the full text of CRITIQUE OF A RISK ANALYSIS AIMED AT ESTABLISHING A SAFE DAILY DOSE OF FLUORIDE FOR CHILDREN, the first draft from which this paper was taken, is available.

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Local anti-fluoride activists tell porkies yet again

FFNZ confuses lack of low fluoride studies on rats with human studies

Well, I suppose that’s not news. A bit surprising, though, because they are claiming the absence of research on fluoridation and IQ – which sort of conflicts with the previous attempts to actually condemn and misrepresent the actual research on fluoridation and IQ.

Fluoride Free NZ’s (FFNZ) face book page is claiming:

Would you be interested to know that no studies have been conducted on fluoridated water at 0.7ppm to determine whether there is IQ reduction? The National Toxicology Program are currently completing research to fill this gap. You would have thought that they would have done this in the 1950s before starting the fluoridation program wouldn’t you?

There have actually been three recent studies from three different countries which have specifically investigated the claim of an effect of fluoridation on IQ – and, unsurprisingly, all threes studies showed there was no effect.

Here are those studies:

New Zealand

Broadbent, J. M., Thomson, W. M., Ramrakha, S., Moffitt, T. E., Zeng, J., Foster Page, L. A., & Poulton, R. (2014). Community Water Fluoridation and Intelligence: Prospective Study in New Zealand. American Journal of Public Health, 105(1), 72–76.

In fact, anti-fluoride activists in the US, as well as New Zealand, have campaigned against this study. Their major criticism is that the study also included the effect of fluoride tablet use. They argue that this makes the unfluoridated control group useless because many participants will have consumed fluoride tablets. However, they ignore the fact that the statistical analysis corrected for this but still found no statistically significant difference in IQ of children and adults from fluoridated and unfluoridated areas.

Sweden

Other critics of the Broadbent et al. (2014) study have raised the issue of experimental power because of the numbers of people in the study. This could be a valid issue as it would determine the minimum effect size capable of being detected. Aggeborn & Öhman (2016) made that criticism of Broadbent et al., (2016) and all other fluoride-IQ studies. Their study is reported at:

Aggeborn L, Öhman M. (2016) The Effects of Fluoride in the Drinking Water. 2016.

Aggeborn & Öhman (2016) used much larger sample size than any of the other studies – over 81,000 observations compared with around 1000 or less for the commonly cited studies. It was also made on continually varying fluoride concentrations using the natural fluoride levels in Swedish drinking waters (the concentrations are similar to those in fluoridated communities), rather than the less effective approach of simply comparing two villages or fluoridated and unfluoridated regions. The confidence intervals were much smaller than those of other cited fluoride-IQ studies. This makes their conclusion that there was no effect of fluoride on cognitive measurements much more definitive. Incidentally, their study also indicated no effect of fluoride on the diagnosis of ADHD or muscular and skeleton diseases.

Canada

Another recent fluoridation-IQ study is that of Barbario (2016) made in Canada:

Barberio, AM. (2016). A Canadian Population-based Study of the Relationship between Fluoride Exposure and Indicators of Cognitive and Thyroid Functioning; Implications for Community Water Fluoridation. M. Sc. Thesis; Community Health Sciences, University of Calgary.

This study also had a large sample size – over 2,500 observations. This reported no statistically significant relationship of cognitive deficits to water fluoride.

Incidentally, Barberio (2016) also found there was no evidence of any relationship between fluoride exposure and thyroid functioning. That puts another pet claim of anti-fluoride campaigners to rest.

Animal studies

So much for NZFF’s claim that “no studies have been conducted on fluoridated water at 0.7ppm to determine whether there is IQ reduction.” But, just a minute, they are quoting the National Toxicology Program (NTP):

“No studies evaluated developmental exposure to fluoride at levels as low as 0.7 parts per million, the recommended level for community water fluoridation in the United States. Additional research is needed.”

But they omit the next sentence from the quote:

“NTP is conducting laboratory studies in rodents to fill data gaps identified in the systematic review of the animal studies.”

The NTP is discussing the research with animals, mainly rats, where effects of fluoride on the cognitive behaviour of the test animals have been reported but the fluoride concentrations are very high. And NTP’s assessment base on the review of the literature found only “a low to moderate level of evidence that the studies support adverse effects on learning and memory in animals exposed to fluoride in the diet or drinking water.” Hence the need for more research.

As part of the NTP’s research, which is currently underway, there are plans to extend studies to low fluoride concentrations more typical of that used in community water fluoridation.

The high concentrations used in animal studies is a major flaw in the anti-fluoride activist use of them to oppose community water fluoridation. For example, Mullinex et al (1995) (very commonly cited by anti-fluoride campaigners) fed test animals drinking water with up to 125 mg/L of fluoride (concentrations near 0.8 mg/L of fluoride are used in community water fluoridation).

While it is unlikely that the NTP research will find any significant effects of fluoride on the cognitive behaviour of rats at the low concentrations used in community water fluoridation the anti-fluoride campaigners have their fingers (and probably toes as well) crossed.

NTP will begin publishing the results of their new research next year (see Fluoride and IQ – another study coming up).

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Fluoridation: Open letter to Democrats for Social Credit

The only New Zealand political party opposing community water fluoridation relies on false information

The only political party in New Zealand campaigning against community water fluoridation is the Democrats for Social Credit. It is a minor party, nor represented in Parliament and of little influence. However, it does have connections with Fluoride Free NZ, the main anti-fluoride activist group, and its members have imposed anti-fluoridation policies on some groups they belong to. Two examples are Grey Power and the Hamilton Residents & Ratepayers Association – both of which presented anti-fluoride submissions to the recent parliamentary health committee hearings.

I wish to promote an open discussion with the Democrats for Social Credit about their anti-fluoridation policy so have sent them this Open Letter. If they are open to a good-faith discussion I am happy to provide space on this blog for an exchange of views on their policy.


David Trantor, Health Spokesperson for Democrats for Social Credit

Dear David Tranter,
Health Spokesman,
Democrats for Social Credit

You wrote an open letter to the Minister of Health critiquing the government’s policy on community water fluoridation (CWF) and posing some questions about dental health programmes, documented evidence relating to CWF and human rights aspects you consider relevant.

Here I take issue with some of your claims – particularly about dental health in Denmark and the scientific evidence supporting CWF. I believe the evidence does not support the anti-fluoridation policy of your party and your party should reconsider that policy.

If you believe my arguments here are mistaken or otherwise wish to defend the current anti-fluoride policy of your party I am open to a good-faith exchange of opinions and offer you the right of reply and the opportunity for a further discussion on this blog.

Natural fluoridation in Denmark

You point to the good dental health in Denmark and assert “they have never fluoridated their water.” This is true – but you ignore the fact that much of the Danish population benefits from natural levels of fluoride in their drinking water.

Unlike New Zealand parts of Denmark have drinking water fluoride concentrations similar to the optimum concentrations recommended for CWF. Map 1 from Kirkeskov et al., (2010) shows the distribution of different drinking water fluoride concentration ranges.  Map 2 shows the population distribution. We can see a significant fraction of the Danish population does have access to drinking water containing fluoride.

Map 1: Distribution of natural drinking water fluoride concentrations in Denmark. The town of Nexo is on the Baltic island of Bornholm – shown in the top left-hand rectangle.

Map 2: Population distribution in Denmark.

These natural levels of drinking water fluoride are beneficial to oral health in Denmark. Here is some data from Kirkeskov et al., (2010) illustrating this. The following graph compares the dental decay (numbers with more than 2 decayed, missing or filled teeth surfaces – dmfs) at various drinking water fluoride concentrations for 5 year-olds born in 1989 and 1999.

As we can see, the extent of decay declines with fluoride concentration.

There is a similar pattern for 15-year-olds born in 1979 and 1989. This figure shows the relative numbers with more than 2 decayed missing or filled teeth surfaces, DMFS, for 15-year-olds.

And the same pattern for 15-year-olds with more than 6 decayed, missing or filled tooth surfaces.

Danish dental health programmes

You refer to a “Nexux” programme and argue that this could be an alternative to CWF in New Zealand.

I think you are referring to the programme run in Nexo – a town on the east coast of the Baltic island of Bornholm, Denmark. It is a successful local dental health programme, but only one of several in Denmark. Nexo was in an area of very low socio-economic status and introduced a dental programme at the end of 1987 aimed at improving the dental health fo children.  Ekstrand & Christiansen, (2005) give this description of the programme:

“Since 1992, the program has been offered to children from the age of 8 months. It is based on three closely interrelated principles applied according to the individual child’s needs: (1) education of parents, children and adolescents in understanding dental caries as a localized disease, (2) intensive training in home-based plaque control and (3) early professional, non-operative intervention, including professional plaque removal, local application of 2% NaF and application of sealants. In the period when the children have erupting permanent first or second molars, the parents and children are instructed in using a tooth brushing technique specially designed for erupting molar teeth.”

As you can see it is a rather intensive programme and is not a Denmark-wide programme. It has been successful in Nexo, where 15-year-olds had DMFS (decayed, missing and filled tooth surfaces) values in 1986 (before introduction of the programme)  slightly higher than the Danish average. The equivalent values of DMFS for Nexo were the third lowest for all municipalities in 1993 and the lowest in 1999 (Ekstrand & Christiansen, 2005).

Elements of the Nexo programme will be used in other parts of Denmark, and in other countries. Especially where school-based programmes exist.

Incidentally, Map 1 indicates the concentration of natural fluoride in the drinking water on the island where Nexo is situated is similar to that recommended for community water fluoridation. Ekstrand et al., (2005) reports that the fluoride concentration in the Nexo drinking water is 0.8 mg/L.

Nexo is a complement to, not a substitute for, CWF

Each country and region adopt health programmes appropriate to their circumstance. In New Zealand, we have programmes which include some aspect of the Nexo programme or similar programmes like the ChildSmile programme in Scotland (see ChildSmile dental health – its pros and cons and ChildSmile – a complement, not an alternative, to fluoridation). For example the use of fluoride varnish treatments, especially in non-fluoridated areas.

New Zealand can learn from the experience of other countries and in practice, we may introduce some aspects of other programmes. But blanket transfer of full programmes is rare.

The important aspect, though, is none of these programmes is considered an alternative to fluoridation. They are considered as complementary to CWF, and not substitutes for CWF.  The Danish Dental Association has supported fluoridation for areas of low natural fluoride concentrations. Similarly, the British Dental Association in Scotland supports both ChildSmile and CWF and has publicly called for communities to move towards introducing water fluoridation.

In fact, we can consider that the programme used in Nexo (where the drinking water contains fluoride at 0.8 mg/L) actually complements the effect of natural community water fluoridation.

“Documented evidence”

You ask the Minister:

“Why do you ignore all the documented evidence against fluoridation instead of applying positive dental health policies such as the Denmark example?”

The “Denmark example” is dealt with above and it is not what you suggest. Similarly, I suggest the “documented evidence” you refer to really doesn’t give the viable argument “against fluoridation” you imply.

Unfortunately, you do not present any of this “documented evidence” for discussion. Perhaps, if you respond positively to my suggestion of a right of reply and an ongoing discussion, you can give this evidence.

“Informed consent”

You refer to the “H&D Commissioner’s Code of Rights” asserting that:

“no-one can be medicated without giving their informed consent” and “people have the right to give – or refuse – their INFORMED consent when fluoridation is applied to public water supplies?”

Well, I am all for people being properly informed and providing consent to the treatments used for their water supply. I see this as a democratic issue and I support democracy.

But you destroy your argument by suggesting fluoridation is a “medication” when it clearly is not – either legally or rationally. The legal argument was surely settled by the High Court decision in 2014 (see Corporate backers of anti-fluoride movement lose in NZ High Court) where Justice Rodney Hansen concluded:

“[80] In my view, fluoridation cannot be relevantly distinguished from the addition of chlorine or any other substance for the purpose of disinfecting drinking water, a process which itself may lead to the addition of contaminants as the water standards themselves assume. Both processes involve adding a chemical compound to the water. Both are undertaken for the prevention of disease. It is not material that one works by adding something to the water while the other achieves its purpose by taking unwanted organisms out.

[81] The addition of iodine to salt, folic acid to bread and the pasteurisation of milk are, in my view, equivalent interventions made to achieve public health benefits by means which could not be achieved nearly as effectively by medicating the populace individually. . . . All are intended to improve the health of the populace. But they do not, in my view, constitute medical treatment for the purpose of s 11″ [the relevant section of the NZBORA].”

Is scientific knowledge  really “one-sided” propaganda

You also weaken your argument by claiming:

“the one-sided propaganda used to support fluoridation is not informing people”

Describing objective scientific research and findings as “one-sided” simply displays your own bias – and willingness to discredit or ignore the science. Again, you do not give specific examples of the science you consider “one-sided propaganda” – hopefully, you will do so if you take up my offer of a right of reply and a continued discussion.

Democratic rights

You assert:

“when fluoridation is forced upon people it is nothing less than mass medication concerning which people have no opportunity to give – or refuse – their consent.”

The common anti-fluoride claim that people are having fluoridated water forced upon them always raises the picture in my mind of a person being held down and water being forced down their throat as in force-feeding.

Of course, that is ridiculous – for a number of reasons.

  • In New Zealand, there has usually been a democratic public consultation of some sort before the introduction of CWF – or even after its introduction. Local bodies have surveyed residents or used referenda. They have also used a consultation procedure relying on submissions from the public.The opportunity “to give – or refuse – their consent” has in most cases been far greater than for most decisions made by our representatives in this democracy of ours. Some voters find it annoying when asked for such consent (preferring their representatives decide) but I firmly believe it important to include the public in controversial decisions – even where the controversy results from scaremongering rather than facts (as it does with CWF).
  • There are alternatives for the minority. This means that democratic decisions made by a community can actually be a win-win situation. The majority get the social policy they want and have voted for. the minority have access to alternatives. In fact, most anti-fluoride activists already use alternatives – they filter their tap water or source a different supply. Some cities already provide “fluoride-free” water sources to help this. Sometimes I think the real motivation of these ideologically driven activists is to deny this social health policy to others rather than any real concern they have for their own access to water.
  • Some activists will acknowledge there is no evidence of any harmful side effects from CWF but invoke a “precautionary principle” to argue against it. They should be mollified by the fact that CWF is one of the most extensively researched topics. In a sense, we must thank the ideologically and commercially motivated anti-fluoride campaigners for this. Their activity is rarely successful in preventing CWF or fooling most of the public. But it does mean that researcher keep an eye on the arguments and are continually checking them out.

Conclusion

David, I believe you are mistaken, or misinformed, about the dental health programmes in Denmark. You ignore completely the availability of effective natural levels of fluoride in much of Denmark’s drinking water and seem unaware of the nature of the Nexo programme or its limited area of operation.

Expert opinion considers programmes like Nexo and the Scottish ChildSmile are effective complements to CWF – not substitutes for, or alternatives to, CWF. I support our health officials considering use of similar programmes in New Zealand but it is misleading for the Democrats for Social Credit to advocate for such programmes simply as a way of preventing or opposing CWF – which is  an effective, beneficial and safe social health measure.

I appreciate you may not accept my arguments or the facts I have presented here. If that is the case I urge you to accept my offer of a right of reply and ongoing good-faith discussion and am happy to help this by making space available on this blog.

I look forward to your response.

References

Ekstrand, K. R., & Christiansen, M. E. C. (2005). Outcomes of a non-operative caries treatment programme for children and adolescents. Caries Research, 39(6), 455–467.

Kirkeskov, L., Kristiansen, E., Bøggild, H., Von Platen-Hallermund, F., Sckerl, H., Carlsen, A., … Poulsen, S. (2010). The association between fluoride in drinking water and dental caries in Danish children. Linking data from health registers, environmental registers and administrative registers. Community Dentistry and Oral Epidemiology, 38(3), 206–212.

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Fluoridation: What’s happening with the New Zealand legislation?

The second reading of the fluoridation bill is now on the order paper for the current parliament. Public submissions have been heard, the Health Committee has reported back to the House and the Ministry of Health (MoH) has provided its own responses to submissions.

Of course, we don’t know yet what the final Act will be like exactly. But the submissions, the committee report, and the MoH responses give us some idea of likely changes to the original bill.

Submissions

I have described before how the anti-fluoride activist groups organise to deluge consultation processes with their submissions. This was certainly the case here and their submissions accounted for most of those opposed to the Bill.

However, because the legislation is about the decision-making process and not the scientific or ethical validity of social health policies simple opposition to fluoridation was irrelevant  – outside the scope of the bill. This was true of most submissions (85%) and these should be considered a waste of every bodies time.

I am surprised the anti-fluoride organisations organising this submission campaign chose to take such an irrelevant approach. Surely if they had put a bit of thought into their efforts they could have directed their submission at relevant aspects such as the consultation process, the decision-making body and the question of referenda.

That said, a small number of the anti-fluoride submissions did address aspects of the bill and these were considered by the Health Committee and the MoH.

Putting aside the anti-fluoride submissions which did not address the bill, 20% percent supported the Bill and 80% opposed to the Bill as currently drafted. Most supported extending fluoridation cover, but disagreed with specific parts of the Bill and suggested changes.

The legislation does not mandate fluoridation

This is a common misunderstanding promoted by anti-fluoride campaigners – obviously attempting to use scare-mongering to motivate their supporters. For example, Fluoride Free NZ formally names the legislation the Mandatory Fluoridation Bill which is dishonest – the correct name of the bill is Health (Fluoridation of Drinking Water) Amendment Bill.”

The bill transfers decision-making from local bodies to District Health Boards (DHBs) – but it does not require DHBs to make a decision about fluoridation. That is up to local DHBs and local conditions such as dental health, likely advantages and establishment costs.

Consideration of other health factors

A number of submitters expressed concern that while the bill requires DHBs to consider dental health effects, consideration of other possible health issues is not provided for. However,  the response from the MoH to this is:

“While DHBs are required to consider the evidence in relation to oral health, DHBs are not prevented from considering other factors, including the effect of fluoridation on overall health. However, officials do not consider it necessary for the Bill to require DHBs to consider these other factors.”

So, consideration of other health factors will depend on specific situations, the board members or public interest. Importantly, DHB’s are not prevented from considering wider health aspects.

Considering the science

I was interested to see that:

” The Ministry of Health is currently exploring options for the ongoing monitoring and assessment of research on fluoridation within the Ministry to align with the implementation of the Bill.”

The MoH sees this as carrying on the role formerly played by the now disbanded National Fluoridation Information Service. But this also goes some way to satisfying a suggestion in my own submission that the assessment of research on fluoridation is carried out by some sort of central expert body (see Fluoride, coffee and activist confusion). My concern was that the DHBs are not really suitable bodies for making expert reviews of the literature and evaluating the current state of the science. Handing this over to a central body could also prevent boards being deluged with misinformation and unsupported claims about the science – a feature of local body consultation which caused so much trouble to councils.

It was the pressure of submission campaigns including misrepresentation and false claims about the science which drove local bodies, who do not have the expertise to consider the science, to request a change to the legislation. DHBs will confront the same situation unless they can direct scientific consultation to a central expert body.

Community consultation

Many submitters (12%), both for and against fluoridation, suggested the bill should specifically require DHBs to consult the community about fluoridation decisions. While the bill did not make such specific requirements it also did not prevent such consultation.

In practice, public consultation will depend on the level of demand for it. It is up to DHBs to decide when consultation is appropriate and there is already a regulatory requirement for DHBs “to foster community participation in health improvement” which could cover that.

There is also provision for the Minister to describe a fluoridation decision as a “significant service change” which would require DHBs to undertake community consultation on regional service plans including fluoridation.

So, the anti-fluoride activist claims of denial of community consultation is wrong. While consultation is not specifically required it is not prevented by the bill and will depend on the level of public interest.

Engagement with local authorities

The health committee is recommending the bill be amended to explicitly require DHBs to consider the views of the drinking water supplier. This accommodates suggestions made by some local bodies who feared the imposition of decisions without considering their local situations.

However, the committee also suggested an amendment to make clear that engagement with local authorities does not require them to consult communities. The DHB which makes the ultimate decision would have that responsibility where necessary.

The Committee also suggested “the Government consider whether
it intends to contribute funding towards the costs of establishing fluoridated water supplies” because there is a “moral hazard arising from the DHBs making a decision that will impose costs on local authorities and ratepayers.”  It looks like the Government has accepted this point as they have already made $12 million dollars available to local bodies setting up new fluoridation systems (see Government commits $12m to help councils cover costs of fluoridation in water supplies.).

Provision of non-fluoridated alternatives

Some local bodies have already introduced “fluoride-free” taps at the request of local anti-fluoride campaigners., The MoH is suggesting an amendment to the bill to make clear that “DHBs can direct local government water supplies in their region on a supply by supply basis if they wish.”

This could make it possible for specific local supplies, like Petone in the Hutt region or some supplies in Christchurch to remain unfluoridated if their communities demand it even if a decision is made to fluoridate a region.

The DHB or the director general of health?

Many of the submitters opposed to the bill in its present form suggest that the decision-maker should not be the DHBs but the Director-General of Health or central government. This is because of the likely low expertise of DHB members, low voter turnout for DHB elections and concerns of legal challenges to DHB decisions. There was also the expressed belief that the anarchic and dishonest coordinated submission campaigns previously experienced by local bodies would simply be transferred to the DHBs.

Some submitter proposed that fluoridation be mandatory thereby removing the need for an elected body to be responsible for the decision making.

The committee report and response from the MoH show that parliament will probably stick with the DHBs as the decision maker. There are some advantages in this (the DHB have responsibilities in health areas) and the proof of the pudding will be in the eating. Will the DHB approach to consultations be able to successfully give more credence to credible and peer-reviewed science than the misinformation and distortions of science promoted by anti-fluoride campaigners?

Possibly. I hope so.

Conclusions

Despite the anti-fluoride campaigns and the resulting deluge of misinformed or misleading submissions, the submission process has been successful. Problems in the current wording of the bill were identified and reasonable solutions to these problems have been advanced.

We should now see how MPs react to the bill and the recommended changes in the second reading. Anti-fluoride activists have carried on an intensive campaign of emails, letters and representations aimed at MPs. On the whole, this will have been counterproductive as MP are surely aware this bill is not about the science or ethics of fluoridation but simply the decision-making process.

I am picking that these campaigns have produced more heat than light and will have little influence on the progress of the bill. However, I do expect a lot of teeth-grinding, hairpulling, garment rending, lamentations that democracy doesn’t work or that various MPs should be shot or otherwise disposed of from anti-fluoride campaigners. This is already happening and will no doubt intensify when the final bill is passed into law.

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Anti-fluoridationists commonly misrepresent Ministry of Health data

Anti-fluoride activists tell porkies about the Ministry of Health’s data on child dental health. They cherry-pick the data to make it appear that community water fluoridation is ineffective. And when challenged to discuss the issue they run away.


I am currently dealing with family issues so am reposting this article, “A challenge to anti-fluoridationers to justify their misrepresentation of New Zealand research”  from April 2016.  It shows how local anti-fluoride activists are misrepresenting the Ministry of Health’s data on child oral health


One of the frustrations I have with the fluoridation issue is the refusal of anti-fluoride activists to engage on the science. They will pontificate, but they won’t engage in discussion.

On the surface, one would think there is a difference of opinion or interpretation of scientific issues and that could be resolved by discussion. Yet local anti-fluoride campaigners refuse to enter into discussion. Again and again, I have offered space here to local anti-fluoride campaigners so that they could respond to my articles and they have inevitably rejected the offer. They have also blocked me, and other people discussing the science, from commenting on any of their social media pages or web sites. Even when they, themselves, call for a debate they reject specific responses I have made accepting that call.

So I am left with the only alternative of responding to their claim with an article here – or on a friendly web or blog site. At least that gives me space to present my argument – I just wish I could get some intelligent responses enabling engagement on the issues.

Misrepresentations repeated

The latest misrepresentation of the science is a claim by the Auckland Fluoride Free NZ Coordinator, Kane Titchener, that recent research proves fluoridation [is] not needed.

It repeats the same misrepresentation made by Wellington Anti-fluoride campaigner, Stan Litras, which I discussed in my article Anti-fluoridation cherry-pickers at it again. Kane has either ignored my article, chosen to ignore it or possibly not even understood it.

So here we go again.

Kane claims:

“A New Zealand study published in Bio Medical Central Oral Health last month shows dental health improved the greatest extent for children in non-fluoridated areas. There is now no difference in dental decay rates between non-Maori children who live in fluoridated areas and non-Maori children who live in non-fluoridated areas, proving that fluoridation is not needed for children to obtain good dental health.”

Although he doesn’t cite the study (wonder why), his use of two figures from the study show he is writing about the paper:

Schluter, P. J., & Lee, M. (2016). Water fluoridation and ethnic inequities in dental caries profiles of New Zealand children aged 5 and 12–13 years: analysis of national cross-sectional registry databases for the decade 2004–2013. BMC Oral Health, 16(1), 21.

His claim relies on the comparison of data for “non-Māori” children in fluoridated and fluoridated areas. No – he doesn’t misrepresent the data – he just ignores the discussion by these authors of problems with simple interpretation of the data for non-Māori because of the fact it is not ethnically uniform. In particular, he ignores the qualifications they place on the data because of the inclusion in non-Māori of data for Pacifica who have poorer dental health than the rest of this group and live predominantly in fluoridated areas. This, in effect, distorts the data by overestimating the poor oral health for “non-Māori” in the fluoridated areas.

The apparent convergence

The data used in this study were taken from the Ministry of Health’s website. This divides the total population of children surveyed into the ethnic groups Māori, Pacific and “Other.” While the “other’ group will not be completely uniform (for example including Pakeha, Asian, other groups) it becomes far less uniform when combined with the Pacific group to form the non-Māori group.

So, Kane salivates over this figure from the paper especially the plots for  non-Māori ethnicities in fluoridated (F) and non-fluoridated (NF) areas.

12903_2016_180_Fig1_HTML

Fig. 1 No obvious decay experience (caries-free) percentages and mean dmft for 5-year old children over years 2004 to 2013, partitioned by Māori and non-Māori ethnicities and fluoridated (F) and non-fluoridated (NF) areas

Yes, that convergence is clear and I can see why Kane is clinging to it – who can blame him. But he completely ignores the warning from the paper:

“It is likely that a substantial driver of this convergence was due to significant changes within the dynamic and heterogeneous non-Māori groups both within and between DHB regions. In effect, the ecological fallacy – a logical flaw whereby analyses of group data are used to draw conclusions about an individual – may be operating within the non-Māori group.”

When the Pacific data is removed (as is the case for the “other” group effectively made up from non-Māori and non-Pacifica) we get the plots below.

Other

Comparison of data for “other” (non-Māori/non-Pacifica) children in fluoridated (F) and unfluoridated (UF) areas.

Nowhere near as useful for Kane’s confirmation bias and the message he wants to promote. OK – there is still some evidence of convergence from about 2007 on between fluoridated and unfluoridated children. But the graphs do show that community water fluoridation is still having  a beneficial effect. And this apparent convergence could be explained by things like the introduction of “hub and spoke” dental clinics after 2004. One problem with this raw data is that children are allocated according to the fluoridation status of the school – rather than their residence. This will lead to incorrect allocation in some cases.

Some data for Pacifica

Just to underline the problems introduced by inclusion of Pacific in the non-Māori group of the study consider the data for Pacifica shown below.

other-pacifica

Data for 5-year-old children. dmft = decayed, missing and filled teeth. The “other” group is non-Māori and non-Pacifica

The oral health of Pacifica is clearly poorer than that of the “other” group.

Also, Pacifica make up about 20% of the non-Māori fluoridated group. So they will influence the data for the non-Māori fluoridated group by reducing the % caries free and increasing the mean dmft.

So Kane, like Stan, is blatantly cherry-picking. He is misrepresenting the study – and its author – by ignoring (or covering up) the qualifications regarding the influence of inclusion of pacific in the non-Māori fluoridated group.

The challenge

Now, I repeat the offer I have made in the past to give a right of reply to both Kane Titchener and Stan Litras. They are welcome to comment here and if they want more space I am happy to give space for separate articles for them in the way I did for the debate with Paul Connett. Now I can’t be fairer than that, can I?

So what about it Stan and Kane? What are your responses to my criticisms of the way you have cherry-picked and misrepresented this New Zealand paper?


NOTE: I have sent emails to both Kane and Stan asking them to respond and offering them right of reply.

UPDATE 1: Great minds and all that – Stan Litras sent out a press release today calling for a nation-wide debate on this issue (see FIND calls for a national debate on fluoridation). However, the seriousness of his request is rather compromised by his reply to my offer of a right of reply to the above article. He did respond to my email very quickly. This is what he wrote:

“Thanks for the offer, Ken, but I have not visited your blog site for a long time, as I object to the way you attempt to defame and discredit me.

You play the man and not the ball, which is not the mark of a reasonable person.

I hope to address that in due course as time permits, but for now I must leave you to indulge yourself without my company.”

So much for his wish for a “national debate” when he will not front up to a critique of his claims about the science.

UPDATE 2: Kane Titchener today also posted a press release today which was the text of the article I discuss in this post (see NZ research proves fluoridation not needed). He also responded quickly to my e-mail. The full text of his response was:

Who is this?”

Rather strange – considering he often pesters me with emails.

So I guess both of them have turned down my offer.

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Fluoridation helps protect adult teeth as well as children’s

Photo credit: Seniors Benefit From Drinking Water Together

Recent research reveals that community water fluoridation benefits adults as well as children.

While research into the effects of fluoridation in adults started earlier than for children, early studies suffered from a lack of information on effects of socioeconomic status and other confounding factors.  Recent studies with adults have been more robust but there is still some confusion – especially since the often cited recent Cochrane systematic survey of the scientific literature on fluoridation was unable to draw conclusions on this because of the strict inclusion criteria used was not suitable.

This new study checked the effects of lifetime access to fluoridation on the dental health of adults from a city in southern Brazil.  It concluded that lifetime access to community water fluoridation is associated with lower tooth decay in adults.

The study is:

Peres, M. A., Peres, K. G., Barbato, P. R., & Hofelmann, D. A. (2016). Access to Fluoridated Water and Adult Dental Caries: A Natural Experiment. Journal of Dental Research, 95(8): 1-7.

The full text of the paper is available here.

The researchers adjusted their data for well-known confounders such as socioeconomic status, the pattern of dental visiting, smoking, educational attainment, income, and age. Use of fluoridated toothpaste was common for all subjects so could not explain the results.

The final data, adjusted fo confounders, showed a greater protection with a longer exposure to fluoridated water. The figure below shows this data for  DMFT (decayed, missing and filled teeth) and DFT (decayed and filled teeth). The use of both measures helps to accommodate the fact that some teeth are missing for reasons other than decay.

The data is present as ratios of DMFT and DFT for the shorter exposure periods ( <50% and 50%-75%) to the values of DMFT and DFT for exposures of >75%.

So, once again a study showing the benefits of community water fluoridation. this time for adults with long time exposure to fluoridation.

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Fluoridation: the truth about heavy metal contamination

Anti-fluoride activists going on about contaminants in drinking water due to fluoridation have it all wrong. If they avoided their knee jerk, chemophobic reactions to certificates of analysis and did some calculations they would realised they are making a fuss about absolutely nothing.


I am currently absorbed in dealing with family issues at the moment so am reposting this article, .” Unfortunately is is still very much relevant.


Sometimes anti-fluoride propagandists end up shooting themselves in the foot. This always seems to happen when they produce “evidence’ that fluoridating chemicals are loaded with toxic heavy metals.

It feels like shooting fish in a barrel to debunk their use of analytical figures because the data they produce always shows them to be completely wrong. I wrote about this before in Fluoridation: emotionally misrepresenting contamination. So, I am effectively repeating myself by discussing the meme image below that Fluoride Free NZ is currently circulating in social media.

Hill lab

Still, this time, I will show how insignificant these analytical figures by comparing the calculated final concentrations in tap water – due to addition of the chemical – with measured concentrations for these contaminants in Hamilton tap water.

Added contaminants as percentage of MAVs

But first – what contribution would this sample of fluorosilicic acid make to the contaminant levels in Hamilton’s tap water – and how do these levels compare with the maximum acceptable values (MAVs) defined in New Zealand’s Drinking Water Standards? The values for the MAVs are published in:

Ministry of Health. (2008). Drinking-water Standards for New Zealand 2005 ( Revised 2008 ) (Vol. 2005). Wellington.

In this table, the “Tap water (mg/L)” data are the calculated final concentrations after addition of the fluoridating agent in the meme. The “%age of MAV” data are these values expressed as a percentage of the maximum acceptable values (MAVs) for the contaminants.

Impurity MAV (mg/L) Tap water calculated (mg/L) %age of MAV
Aluminium 0.1 8.69E-05 0.0869
Antimony 0.02 < 3.56E-07 <0.0018
Arsenic 0.01 1.26E-05 0.1264
Barium 0.7 4.27E-06 0.0006
Cadmium 0.004 2.37E-07 0.0059
Chromium 0.05 4.74E-06 0.0095
Copper 1 1.19E-06 0.0001
Iron 0.2 1.62E-04 0.0810
Lead 0.01 2.37E-07 0.0024
Manganese 0.04 3.56E-06 0.0089
Mercury 0.007 < 1.98E-07 <0.0028
Molybdenum 0.07 < 3.56E-07 <0.0005
Nickel 0.08 3.95E-06 0.0049
Selenium 0.01 < 1.98E-07 <0.0020
Uranium 0.02 2.05E-06 0.0103

Sorry, I have had to use scientific formating for some numbers because the final calculated concentrations in tap water are so low. On average, the calculated concentration  of these contaminants due to the fluoridating agent is about 0.02% of the MAV.  The largest relative contribution is for arsenic – just over 0.1%.

Regulations require that the contribution of contaminants from fluoridating agents should always be less than 10% of the MAV . The actual level of contaminants in this particular sample is well below those regulated maxima.

The Fluoride Free NZ meme is just promoting naive chemophobic scaremongering about absolutely nothing. These activists just haven’t bothered calculating what the analytical data means for the final concentrations in tap water. Or even bothered comparing the data with the regulated maximum amounts allowed for fluoridating chemicals. These values are available in Standard for the Supply of Fluoride for Use in Water Treatment.

Added contaminants as a percentage of concentrations in inlet water and treated water.

Let’s now compare the estimated contribution from contaminants in this sample of fluorosilicic acid to the levels of the very same contaminants in the Hamilton water. I have taken data from this document issued by the Hamilton City Council:

Waikato River and Treated Drinking Water Comprehensive Analysis Report 2013/14

The next table is for samples taken on 18th July 2013 at the intake to the treatment plant (that is the source water before treatment). The “Added FSA%” is the calculated level of impurity resulting from fluoridation expressed as a percentage of the impurity naturally present in the source water.

Impurity Intake (mg/L) Added FSA%
Aluminium 1.68E-01 0.05
Antimony 8.50E-04 <0.04
Arsenic 1.96E-02 0.06
Barium 1.88E-02 0.02
Berylium <1.10E-04 0.18
Cadmium <5.30E-05 0.45
Chromium <5.30E-04 0.89
Copper <5.30E-04 0.22
Iron 2.94E-01 0.06
Lead 1.18E-04 0.20
Manganese 2.15E-02 0.02
Mercury <8.00E-05 <0.25
Molybdenum 3.80E-04 <0.09
Nickel <5.30E-04 0.75
Selenium <1.10E-03 <0.02
Tin <5.30E-04 0.22
Uranium <2.10E-05 9.78
Zinc 8.13E-01 0.00

Now, a similar calculation and comparison – this time “Added FSA%” is the calculated level of impurity resulting from fluoridation expressed as a percentage of the impurity already present in the “treated water” – which is the final tap water. (At this time the Hamilton water supply was not fluoridated).

Impurity Treated (mg/L) Added FSA%
Aluminium 2.04E-02 0.43
Antimony 8.00E-04 <0.04
Arsenic <1.10E-03 1.15
Barium 1.26E-02 0.03
Berylium <1.10E-04 <0.18
Cadmium <5.30E-05 0.45
Chromium <5.30E-04 0.89
Copper 8.00E-04 0.15
Iron <2.10E-02 0.77
Lead 4.82E-04 0.05
Manganese 1.75E-03 0.20
Mercury <8.00E-05 <0.25
Molybdenum 3.70E-04 <0.10
Nickel 3.52E-03 0.11
Selenium <1.10E-03 <0.02
Tin <5.30E-04 0.22
Uranium <2.10E-05 9.78
Zinc 4.82E-03 0.14

The extremely low levels of contaminants – both calculated and already in the intake water and final treated water – mean some of the calculations are rather meaningless. Especially as some of the analysed values are given as less than the detection limit.

However, the very low calculated contribution of contaminants from this fluorosilicic acid sample – usually < 1% of that naturally present – shows how ridiculous the Fluoride Free NZ claims about contamination introduced by fluoridating agents is.

Never trust anti-fluoride campaigners

Fluoride Free NZ is simply scaremongering – relying on naive chemophobia where just the chemical name and analytical data (even where the “<” symbol indicates below the level of detection) seem to scare people.

This example illustrates, once again, that the claims made by anti-fluoride and similar activists should never be accepted at face value. They should always be checked against reliable sources.

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Bottle fed infants: fluoridated water not a problem

Parents need no longer be concerned about using fluoridated water for baby formula. Photo credit: Life insurance for your heirs

New recommended fluoride dietary intakes by infants and young children in Australia and New Zealand were recently published. The updated values are available online at Nutrient Reference Values for Australia and New Zealand.

This is a regular update – the Australian National Health and Medical research council advises these recommendations be reviewed every 5 years. But the new recommendations are interesting because the upper limit for fluoride intake for infants and young children is substantially higher than the previously recommended upper limit.

Public health policy in Australia and New Zealand aims to adjust fluoride intake at the population level to be high enough to prevent dental caries but low enough not to cause moderate or severe dental fluorosis or other adverse effects. But health professionals have noted an anomaly in recent years.  Dietary intake of fluoride by children may exceed the previously recommended upper levels – even when community water fluoridation levels are within the recommended targets. Despite this the occurrence of moderate or severe dental fluorosis in Australia and New Zealand was rare.

This led to health authorities acknowledging that, for example, bottle-fed infants may sometimes exceed the upper limits for dietary fluoride intake – but still recommending this was harmless. Anti-fluoride activists misrepresented this advice by claiming health authorities were recommending that fluoridated water not be used for preparing formula for bottle feeding. Their claims are incorrect and alarmist. The “warning” simply provided advice that there was no risk of harm but the if parents were concerned they should occasionally use non-fluoridated water to make up baby formula.

In part, this current report is a response to that conundrum.

Why the change?

Anti-fluoride propagandists will no doubt attack this change. They have made capital out of the situation in the past by claiming that infants and young children are getting dangerous levels of fluoride in their diet. They, of course, ignore or hide the fact that despite this, levels of moderate and severe dental fluorosis have not been a problem. They, also misrepresent the situation regarding dental fluorosis and its causes – see Dental fluorosis: badly misrepresented by FANNZ and Water fluoridation and dental fluorosis – debunking some myths.

However, the expert working group who reviewed the literature and came up with the new recommendations did have their reasons. And these were more than just the absence of moderate and severe dental fluorosis.

They also concluded the previous recommendation was not consistent. This is because it was based on the US Environmental Protection Agency’s use of mean dietary intake and not the higher percentile fluoride intake which should have been used for the upper limit.

Consequently, their recommendation for the upper limit of fluoride intake for children up to 8 years of age is 0.20 mg F/kg bw/day (kg bw = kg body weight). The previous limit was 0.1 F/kg/ bw/day. This produces the following upper limits for children of different ages.

In Australia and New Zealand, the estimated upper range of total daily fluoride intake for different age groups ranges from 0.09to 0.16 mg F/kg bw/day – considerably lower than the new recommended upper limit of 0.2 mg F/kg bw/day.

Conclusion

Will anti-fluoride campaigners top claiming that bottle-fed infants consume dangerous levels of fluoride if their formula is made with fluoridated water?

And the rest of us should not longer make the concession that intake levels are above the recommended upper limits – because they aren’t.

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No, fluoridation is not associated with leading causes of death

We are all going to die but fluoridation isn’t killing us.

Oh, dear – the local anti-fluoridation people are at it again. More cases of fiddling statistics  – and yet again the guilty party is the US anti-fluoridation activist Karen Favazza Spencer. She should really take some advice about statistics.

Although I suspect she doesn’t care – she is just once again cherry picking in an attempt to paint a bad picture of community water fluoridation.

In this case, she claims the death rates for the leading causes of death in the USA are up to 30% higher in the more fluoridated states than in the less fluoridated ones. And here is her cherry-picked table to “prove it.

Her conclusions are wrong, of course. Look at what we find if we use the data for all the states instead of a few selected ones,  and look at it for signs of any correlation between fluoridation extent and death rates? The data is readily available.

I have done this and found a statistically significant correlation in only one case – cancer. Here is that data and the regression line accounts for about 10% of the variance in cancer rate. Obviously, other factors are involved.

But, wait – there is more. As I explained in my last post Anti-fluoridationists exploit infant deaths by fiddling statistics such statistically significant associations often disappear when other important factors are included in the regression analysis.

So let’s look at what happens when we include mean state elevation in the statistical analysis. As I explained last time there is an association between fluoridation extent and mean state elevation which means that fluoridation is often acting as a proxy for elevation in statistical analyses. Multiple regressions including both fluoridation extent and mean state elevation picks this up.

This table shows the results of such multiple regressions.

Table: Association of death cause with fluoridation extent and mean state elevation. Results from a multiple regression

Fluoridation 2014

p value

Mean altitude

p value

Amount of variance accounted for (%)
Heart disease 0.542 NS 0.007 ** 19.7
Cancer 0.363 NS <0.001*** 38.6
Stroke 0.955 NS 0.180 NS 4.4
Alzheimer’s 0.274 NS 0.834 NS 3.3
Diabetes 0.955 NS 0.445 NS 1.4
Kidney disease 0.441 NS 0.017* 16.3

What does that tell us? Well, the apparent association of cancer death rates with fluoridation is false – it disappears when altitude is included.

None of the death rates for any of the causes of death had a statistically significant association with fluoridation. But heart disease, cancer, and kidney disease were significantly associated with altitude. These associations accounted for from 16% to 39% of the variances in the death rates. The role of mean state altitude may have something to do with the size of cities or possibly improved health at higher elevations (the death rates declined with elevation for all causes considered).

I can only finish with the same words of warning I used last time:

“So, once again the lesson is – never take at face value the claims made by anti-fluoridation activists – no matter how “sciency” their information looks or what data they invoke to “prove” them.

Always check such claims for yourself.”

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